Table 2. Humanized 18F-PEG6-IPQA Residence Times (Hours) in Nonhuman Primates.
| Organ | Female | Male | All |
|---|---|---|---|
| Blood | 0.48 0.25 | 0.33 ± 0.13 | 0.41 ± 0.20 |
| Brain | 0.024 ± 6 0.006 | 0.023 ± 0.005 | 0.024 ± 0.005 |
| Gallbladder | 0.32 ± 0.18 | 0.15 ± 0.09 | 0.24 ± 0.16 |
| Heart | 0.011 ± 0.003 | 0.010 ± 0.002 | 0.011 ± 0.002 |
| Kidneys | 0.17 ± 0.14 | 0.061 ± 0.037 | 0.12 ± 0.11 |
| Liver | 0.29 ± 0.11 | 0.25 ± 0.16 | 0.27 ± 0.13 |
| Lungs* | 0.049 ± 0.025 | 0.034 ± 0.013 | 0.041 ± 0.020 |
| Red marrow* | 0.018 ± 0.009 | 0.012 ± 0.005 | 0.015 ± 0.007 |
| Small intestine | 0.24 ± 0.16 | 0.35 ± 0.19 | 0.29 ± 0.17 |
| Remainder of body | 1.2 ± 0.32 | 1.68 ± 0.11 | 1.46 ± 0.32 |
| Urinary bladder contents | 0.024 ± 0.089 | ||
| Total residence time | 2.45 ± 0.19 | 2.75 ± 0.12 | 2.64 ± 0.22 |
Lung and red marrow times are derived from blood residence time. Data are presented as mean ± SD.