Table 3. Reported cases of TIO located in the hand.
Authors and year | Age/gender | Tumor location | Tumor size (cm3) | Mass found before surgery (years) | Duration of osteo-malacia | Clinical manifestations | Serum phosphate (mmol/L, reference 0.89–1.6) | Serum alkaline phosphatase U/L) [reference 0–130] | Urinary phosphate (mmol/24 h) [reference 23–48] | Recovered from osteomalacia after surgery (months) | Follow-up result | Original pathologic diagnosis | Revised pathologic diagnosis |
Yoshikawa et al., 1977[36] | 18/M | Fourth metacarpal | NA | 5 | 5 | Difficulty in walking, pain in the lumbar region and knees | 0.45 | 63 | 17.1 | 3 | No recurrence | Osteoblastoma | Osteoblastoma and osteosarcoma |
Weidner et al., 1987[18] | 34/M | Mid palm | 9 | 5 | 1 | Back stiffness, lower extremity weakness, waddling gait | 0.51 | Elevated | 24.32 | 3 | No recurrence in 2 years | Giant cell variant of soft part chondroma | PMTMCT |
Folpe et al., 2004[1] | 61/F | Hand | 12 | NA | 6 | NA | NA | NA | NA | NA | No recurrence in 4 years | Giant cell tumor of tendon sheath | PMTMCT |
54/F | 4th finger | Small | NA | 5–6 | NA | NA | NA | NA | NA | No recurrence in 3 years | Atypical enchondroma | Enchondroma with cytologic atypia | |
61/F | Metacarpal | NA | NA | NA | NA | NA | NA | NA | NA | NA | Atypical giant cell tumor | PMTMCT | |
Jacob et al., 2007[37] | 59/M | Index finger | 2 | 2 | 2 | Pain in the lumbar spine, sacroiliac joints, and hips; difficulty in rising and climbing stairs | 0.58 | 436 | 25.6 | 6 | No recurrence | PMTMCT | PMTMCT |
Current case | 45/F | First metacarpal | 14 | 4 | 3.5 | Serious bone pain of whole body, immobility (could nottumoverinbed), and pathological fractures of the hip | 0.35 | 178 | 28.62 | 1 | No recurrence in 1.5 years | Giant cell tumor of tendon sheath | PMTMCT |
NA, not available. PMTMCT, phosphaturic mesenchymal tumor mixed connective tissue variants.