Fig. 3.

Immunohistochemical study of the thoracic cord from the control group 4 weeks after surgical procedures. Spinal cord section demonstrated double immunofluorescence of GFAP (green), MAP-2 (red) and cell nuclei (blue). In the control-group, few neuronal cells were observed in the glial scar. In the BMSC-group, neuronal cells migrated toward the glial scar from the region rostral of lesion site. MAP-2-positive cells (arrows). GFAP-positive cells (arrowheads). In the PEG-group, a few neuronal cells were observed in the glial scar compared to control-group. MAP-2-positive cell (arrow). In the BMSC+PEG-group, many neuronal cells had aggressively migrated toward the glial scar from the region rostral of the lesion site, which was significantly different from the control-group. MAP-2-positive cells (arrows). GFAP-positive cells (arrowheads). Bar=750 µm