Table 1. Single-nucleotide polymorphisms (SNPs) among microRNA (miRNA) sequences, miRNA processing genes, and miRNA-binding sites that are significantly associated with cancer risk.
| SNP category | Gene | SNP ID | Variants | Cancer | Association |
| miRNA sequence | |||||
| miR-146a | rs2910164 | G/C | Thyroid | 0.50(0.28, 0.89) | |
| Esophageal | 2.39(1.36,4.20) | ||||
| miR-219-1 | rs213210 | T/C | Esophageal | 1.66(1.00,2.74) | |
| miR-124-1 | rs531564 | C/G | Esophageal | 8.79(1.06, 73.17) | |
| miR-26a-1 | rs7372209 | C/T | Esophageal | 1.35(1.04, 1.76) | |
| miR-631 | rs5745925 | CT/- | Esophageal | 1.57(1.03,2.41) | |
| miR-423 | rs6505162 | C/A | Esophageal | 0.57(0.44, 0.73) | |
| miR-196a2 | rs11614913 | C/T | Esophageal | 1.73(1.16, 2.56) | |
| Lung | 1.25(1.01, 1.54) | ||||
| Glioma | 0.74(0.56, 0.98) | ||||
| miR-27a | rs895819 | G/A | Breast | 0.88(0.78, 0.99) | |
| Gastric | 1.48(1.06, 2.05) | ||||
| miR-218 | rs11134527 | A/G | Cervical | 0.72(0.52, 0.99) | |
| miR-34b/c | rs4938723 | T/C | Hepatocellular | 1.37(1.06, 1.78) | |
| Bio-genesis pathway | miR-499 | rs3746444 | A/G | Head and neck | 0.83(0.69, 0.99) |
| GEMIN3 | rs197414 | A/C | Bladder | 2.40(1.04, 5.56) | |
| Esophageal | 1.45(1.02,2.06) | ||||
| GEMIN4 | rs7813 | T/C | Renal cell | 0.68(0.47, 0.98) | |
| Ovarian | 0.71(0.57, 0.88) | ||||
| GEMIN4 | rs2740348 | G/C | Renal cell | 0.67(0.47, 0.96) | |
| GEMIN4 | rs2740349 | A/G | Ovarian | 0.70(0.51, 0.96) | |
| GEMIN4 | rs2740351 | A/G | Ovarian | 0.71(0.57, 0.87) | |
| XP05 | rs11077 | A/C | Esophageal | 1.84(1.16,2.93) | |
| XP05 | rs2257082 | G/A | Ovarian | 0.73(0.54, 0.99) | |
| RAN | rs14035 | C/T | Esophageal | 1.93(1.09,3.40) | |
| AG01 | rs636832 | A/G | Lung | 0.67(0.53, 0.84) | |
| DDX20 | rs197383 | A/G | Ovarian | 0.69(0.48, 0.99) | |
| Binding sites | RNASEN | rs4867329 | G/A | Ovarian | 0.71(0.51,0.99) |
| CD86 | rs17281995 | G/C | Colorectal | 2.93(1.29, 6.67) | |
| LAMB3 | rs2566 | C/T | Cervical | 1.57(1.25, 1.96) | |
| SET8 | rs16917496 | C/T | Breast | 1.66(1.06,2.61) | |
| ATG4A | rs5973822 | A/G | Ovarian | 0.42(0.24, 0.75) | |
| UGT2A3 | rs17147016 | T/A | Ovarian | 1.47(1.08,2.01) | |
| COL18A1 | rs7499 | G/A | Ovarian | 1.47(1.07, 2.02) | |
| CAV1 | rs9920 | A/G | Ovarian | 1.50(1.04,2.17) | |
| IL1R1 | rs3917328 | G/A | Ovarian | 1.65(1.03, 2.64) | |
| KRAS | rs10771184 | T/A | Ovarian | 1.26(1.01, 1.57) | |
| E2F2 | rs2075993 | A/G | Ovarian | 1.24(1.00, 1.54) | |
| IQGAP1 | rs1042538 | A/T | Breast | 0.42(0.61,0.99) |
The data for association are presented as odds ratio (95% confidence interval).