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. 2011 Jul;30(7):472–481. doi: 10.5732/cjc.011.10157

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Chinese Journal of Cancer

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission.

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Figure 7. — A shows the orthotopic model of pancreatic cancer metastasis. Mice were killed 6 weeks after GFP-expressing ASPC-1 cells were injected into the pancreas of NGS mice. GFP-positive tissues indicate tumor and its metastases in different organs (noticeably lymph nodes and liver). B shows expression of Hh target gene GM, indicating activation of hedgehog signaling pathway during pancreatic cancer metastasis. C shows the percentage of mice with lymph node metastases of tumor in two groups (control or CycT-treated), with 10 mice in each group.