Figure 2. Oxaliplatin induces autophagy in gastric cancer MGC803 cells.

MGC803 cells stably expressing green fluorescent protein-fused LC3 (GFP-LC3) were exposed to 5 and 20 µg/mL oxaliplatin for 24 h. A, dotted accumulation of LC3 was observed by fluorescence microscopy, suggesting the accumulation of autophagosomes. B, the increase of LC3-II protein was detected by Western blotting, indicating cell autophagy.