Figure 3. Oxaliplatin inhibits the phosphorylation of Akt and mammalian target of rapamycin (mTOR) in gastric cancer MGC803 cells.

MGC803 cells were exposed to 20 µg/mL oxaliplatin for 8 h and 24 h. Down-regulation of p-Akt and p-mTOR proteins was detected by Western blotting, suggesting that oxaliplatin inhibits the activation of Akt and mTOR.