Table 1.
Characteristics and MBL genotypes of 72 patients with ASCT
| AA Patients (%) n = 53 | AO/OO Patients (%) n = 19 | P-value* | |
|---|---|---|---|
|
Gender |
|
|
|
| Male |
30 (56.6) |
12 (63.2) |
0.62 |
| Female |
23 (43.4) |
7 (36.8) |
|
|
Mean age (SD), years |
51.6 (13.9) |
50.2 (14.8) |
0.70 |
|
Underlying disease |
|
|
0.78 |
| MM |
14 (26.4) |
6 (31.6) |
|
| HD |
8 (15.1) |
5 (26.3) |
|
| NHL |
22 (41.5) |
7 (36.8) |
|
| AMN |
7 (13.2) |
1 (5.3) |
|
| PL |
1 (1.9) |
0 |
|
| Amyloidosis |
1 (1.9) |
0 |
|
|
Active disease** |
|
|
0.22 |
| YES |
11 (20.8) |
7 (36.8) |
|
| NO | 42 (79.2) | 12 (63.2) |
*Two-tailed Chi-squared test/Fisher exact test for categorical variables or two-tailed t-test for continuous variables.
**Active pre-transplant hematologic disease.
MM: multiple myeloma, HD: Hodgkin disease, NHL: non Hodgkin lymphoma, AMN: acute myeloid neoplasia, PL: prolymphocytic leukemia, ME: multiple sclerosis.
AA genotype: patients homozygous for wild-type structural allele (A).
AO/OO genotype: patients heterozygous or homozygous for the B, C or D alleles.