Table 2.
Summary of World Health Organization (WHO) classification of soft tissue tumors of the neck
| Histologic type | Benign | Intermediate, locally aggressive | Intermediate, rarely metastasizing | Malignant |
|---|---|---|---|---|
| Adipocytic |
Lipoma and its variants (lipoblastoma, hibernoma, lipomatosis) |
Atypical lipomatous tumor, well-differentiated liposarcoma |
… |
Liposarcoma |
| Fibroblastic/myofibroblastic |
Fibromatosis colli, myofibroma, giant cell angiofibroma |
Desmoid-type fibromatosis |
Solitary fibrous tumor hemangio-pericytoma, inflammatory myofibroblastic tumor (inflammatory pseudotumor) |
Fibrosarcoma |
| So-called fibrohistiocytic |
Benign fibrous histiocytoma, diffuse-type giant cell tumor (pigmented villonodular synovitis) |
… |
Giant cell tumor of soft tissues |
Malignant fibrous histiocytoma (undifferentiated pleomorphic sarcoma) |
| Skeletal muscle |
Rhabdomyoma |
… |
… |
Rhabdomyosarcoma |
| Smooth muscle |
Leiomyoma, angioleiomyoma |
… |
… |
Leiomyosarcoma |
| Vascular |
Hemangioma, lymphangioma |
Kaposiform hemangioendothelioma |
Kaposi sarcoma |
Angiosarcoma |
| Perivascular |
Glomus tumor, myopericytoma |
… |
… |
Malignant glomus tumor |
| Chondro-osseous |
Soft tissue chondroma |
… |
… |
Mesenchymal chondrosarcoma, extraskeletal osteosarcoma |
| Uncertain differentiation | Myxoma | … | Ossifying fibro-myxoid tumor | Synovial sarcoma, alveolar soft part sarcoma, primitive neuroectodermal tumor, Ewing sarcoma |
Source- Reference [19].