Table 1.
Sensitivity, specificity, positive (PPV) and negative predictive values (NPV) estimated on sera of stool culture positive campylobacteriosis patients and healthy blood donors
| Antigen | Sensitivity [%] | Specificity [%] | PPV [%] | NPV [%| | ||||
|---|---|---|---|---|---|---|---|---|
| IgA | IgG | IgA | IgG | IgA | IgG | IgA | IgG | |
| OMP18 ELISA | 57.1 | 51.9 | 90.5 | 90.8 | 82.1 | 79.4 | 73.6 | 73.4 |
| P39 ELISA | 40.7 | 57.4 | 90.9 | 90.5 | 75.9 | 81.6 | 68.6 | 74.4 |
| OMP18 + P39 ELISA | 38.9 | 47.3 | 91.0 | 90.8 | 75.0 | 78.8 | 68.3 | 70.4 |
| MOMP MG | 18.3 | 3.3 | 100 | 96.3 | 100 | 40.0 | 62.0 | 57.0 |
| PEB4 MG | 16.7 | 3.3 | 100 | 98.8 | 100 | 66.7 | 61.5 | 57.7 |
| PEB2 MG | 3.3 | 1.7 | 100 | 100 | 100 | 100 | 57.9 | 57.6 |
| PEB1 MG | 0.0 | 1.7 | 100 | 97.5 | - | 33.3 | 57.1 | 56.9 |
| OMP18 MG | 41.7 | 36.7 | 100 | 98.8 | 100 | 95.7 | 69.6 | 67.5 |
| P39 MG | 41.7 | 45.0 | 98.8 | 86.3 | 96.2 | 71.0 | 69.3 | 67.6 |
| Index MG | 56.7 | 50.0 | 98.8 | 83.8 | 97.1 | 69.8 | 75.2 | 69.1 |
| WCL | 28.6 | 48.6 | 96.2 | 83.8 | 76.9 | 58.6 | 75.0 | 77.2 |
OMP18 outer membrane protein 18 kDa, P39 protein 39 kDa, MOMP major outer membrane protein, PEB1-4 perplasmic-binding proteins 1–4, Index MG numerical index for test evaluation that is the sum of the ascribed points of all positive antigens, i.e. bands with coloration more intense than the cut-off band, WCL whole cell lysate