Table 2.
Functional and structural hemodynamic parameters in patients and volunteers
| Pompe patients (n = 84) | Volunteers (n = 179) | P-value | |
|---|---|---|---|
| Mean arterial pressure (mmHg) | 100 (90-111) | 92 (84-103) | <0.001 |
| Heart rate (beats per minute) | 75 (68-83) | 65 (59-71) | <0.001 |
| Diameter carotid artery (mm) | 6.6 (6.1-7.3) | 7.1 (6.5-7.8) | <0.001 |
| Intima media thickness (μm) | 582 (514-683) | 592 (506-695) | 0.68 |
| Distensibility coefficient (10−3/kPa) | 2.9 (1.9-4.1) | 2.7 (2.2-4.1) | 0.72 |
| Carotid-femoral pulse wave velocity (m/s) | 8.8 (7.1-10.7) | 7.4 (6.6-8.6) | <0.001 |
| Central pulse pressure (mmHg) | 38 (31-47) | 36 (31-43) | 0.30 |
| Augmentation index (%) | 21.7 (13.2-30.3) | 19.4 (8.5-29.4) | 0.23 |
| Aortic reflexion time (ms) | 140 (132-149) | 144 (135-159) | 0.02 |
Continuous variables are given as medians with interquartile ranges (IQR). The diameter of the carotid artery was measured in 179 volunteers and 84 patients; IMT was measured in 179 volunteers and 83 patients; the distensibility coefficient was measured in 176 volunteers and 80 patients; cfPWV was measured in 171 volunteers and 79 patients; and PPc, Aix and ATr were measured in 178 volunteers and 83 patients