Table 2.
The frequency of genotypes and alleles of the −930A>G polymorphism of the CYBA gene in the groups of patients (CAD) and blood donors (BD)
| Genotype, Allele | CAD (n = 240) % (n) | BD (n = 240) % (n) | OR (95 % CI), P univariate analysis | |
|---|---|---|---|---|
| AA | 10.4 (25) | 19.2 (46) | Versus AG+GG | 0.49 (0.29–0.82), 0.007 |
| AG | 51.7 (124) | 47.1 (113) | – | |
| GG | 37.9 (91) | 33.7 (81) | Versus AA+AG | NS |
| AA+AG | 62.1 (149) | 66.3 (159) | Versus GG | NS |
| GG+AG | 89.6 (215) | 80.8 (194) | Versus AA | 2.03 (1.21–3.44), 0.007 |
| −930A | 36.2 (174) | 42.7 (205) | Versus −930G | NS |
| −930G | 63.8 (306) | 57.3 (275) | Versus −930A | NS |
CAD coronary artery disease patients, BD blood donors, NS no significance