Figure 3.

Associative memory is impaired in CORT-treated mice in one-trial contextual fear conditioning. Contextual fear conditioning was produced by placing a mouse in the conditioning chamber and delivering one footshock 180 s later. Mice were returned to the conditioning chamber 24 h later to assess for context-elicited freezing. During Day 2, context-elicited freezing was analyzed for each minute of the test (ANOVA with repeated measures) (A) and during the whole session (B). Values are mean ± s.e.m., n = 5–7 animals per group ^**p < 0.01 vs. vehicle group.