FIG 4.
The number of total mast cells (MCTot) and mast cells positive for both tryptase and chymase (MCTC), and the ratio of MCTC/MCTot in the lamina propria (LP) and epithelium, the number of activated mast cells in LP, and the relative mRNA expression level of prostaglandin D synthase (PGDS) in tissues from controls and eosinophilic and non-eosinophilic chronic rhinosinusitis with nasal polyps (CRSwNP). Mast cell phenotype was assessed by detecting tryptase-positive and, on a consecutive section, chymase-positive cells. HPF, high-powered field; IHC, immunohistochemistry; Eos CRSwNP, eosinophilic CRSwNP; Non-Eos CRSwNP, non-eosinophilic CRSwNP.