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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Circ Cardiovasc Genet. 2014 Jan 6;7(1):23–32. doi: 10.1161/CIRCGENETICS.113.000259

Figure 2.

Figure 2

Age-related gene expression profiling in Pitx2 mutants. (A) Clustering analysis of gene expression profile across three time points in control and Pitx2 mutant hearts. Expression patterns of five representative groups are shown in heat map. The color bar represents relative expression level for each gene across different samples. (B) Differential expression between Pitx2 mutant and control across three time points. Mean value for each group was used to calculate fold change between mutants and controls. Box plots for selected clusters show median (middle line), third and first quartile (top and bottom hinges of the boxes), whiskers and outliers (black dots). (C) Gene ontology analysis of genes in each group. GO terms related to biological process and molecular function categories.