Table 2. Properties of Intraoperative and Postoperative Analgesia in Three Groups a, b, c.
Time | Sufentanil | Fentanyl | Placebo | p1 | p2 | p3 |
---|---|---|---|---|---|---|
Analgesia time, min | 171 ± 19 | 168 ± 28 | 122 ± 20 | 0.0001 | 0.0001 | 0.542 b |
Effective analgesia time, min | 214 ± 22 | 163 ± 21 | 146 ± 14 | 0.0001 | 0.012 | 0.0001 |
Immobilization time, min | 226 ± 27 | 209 ± 14 | 159 ± 17 | 0.0001 | 0.0001 | 0.009 |
First opioid request, hr | 4.9 ± 1.3 | 4.2 ± 2 | 3.8 ± 1.1 | 0.0001 | 0.156 b | 0.057 b |
Dose of opioid, mg | 1 ± 0.6 | 1.1 ± 0.3 | 2 ± 0.6 | 0.0001 | 0.024 | 0.75 b |
Pain Score, VAS | ||||||
1st hour | 1.6 ± 0.7 | 3 ± 1.2 | 3.3 ± 1 | 0.0001 | 0.341 b | 0.0001 |
2nd hour | 3.9 ± 1.8 | 4.6 ± 1.6 | 5.7 ± 1.7 | 0.0001 | 0.0001 | 0.0001 |
6th Hour | 4.5 ±2 | 5.4 ± 1.8 | 6.9 ± 2.7 | 0.0001 | 0.0001 | 0.004 |
12th hour | 5.4 ± 2 | 5.5 ± 2.1 | 7.7 ± 3 | 0.0001 | 0.0001 | 0.033 |
18th hour | 5.2 ± 1.8 | 5.9 ± 1.6 | 7.8 ± 1.9 | 0.0001 | 0.0001 | 0.0001 |
24th hour | 5.7 ± 1.2 | 6.3 ± 1.9 | 7.3 ± 2 | 0.0001 | 0.003 | 0.012 |
a data are presented as Mean ± SD.
b VAS, Visual Analogue Scale; p1, Sufentanil vs. Placebo; p2, Fentanyl vs. Placebo; p3, Sufentanil vs. Fentanyl.
c P value > 0.05.