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. 2014 Mar 19;68(5):575–580. doi: 10.1038/ejcn.2014.30

Table 2. Total and individual scores of gastrointestinal symptoms in the 24 and 48 h following consumption of dairy desserts containing 35 g dextrose (control dessert) or different mixtures of maltitol and scFOS in the ITT population (n=36).

    Control Dextrose 24 scFOS 11 Maltitol 35 Maltitol 30 scFOS 5 Maltitol 24 scFOS 11 Maltitol 17.5 scFOS 17.5 Dessert effect (P-value)
0–24 h Total score 3.15±4.26a 6.46±5.85b 8.86±6.49b,c 8.53±7.10b,c 9.41±6.99b,c 10.80±7.98b,c <0.0001
  Flatulence 1.21±1.49 2.11±2.26 3.37±2.56* 2.74±2.50* 3.68±2.46* 4.11±2.34* <0.0001
  Borborygmi 0.70±1.31 1.49±2.01 2.11±2.40* 2.41±2.43* 1.85±2.30* 2.43±2.40* <0.0001
  Bloating 0.70±1.69 1.40±2.20 1.60±2.24 1.74±2.15 1.82±2.41 2.17±2.72* 0.0312
  Discomfort 0.55±1.68 1.46±2.41 1.77±2.44* 1.65±2.98 2.06±2.95* 2.09±2.70* 0.0135
                 
24–48 h Total score 0.88±1.71a 2.34±3.55a,b 3.60±5.39b 2.62±3.57b 2.24±3.37a,b 2.71±4.26b 0.0063
  Flatulence 0.27±0.80 0.83±1.50 1.37±1.99* 1.12±1.61* 1.06±1.54* 1.20±1.78* 0.0037
  Borborygmi 0.30±0.81 0.31±0.93 0.74±1.60 0.79±1.49 0.44±1.13 0.57±1.29 0.0823
  Bloating 0.12±0.55 0.49±1.17 0.69±1.64 0.35±0.92 0.47±1.02 0.57±1.36 0.2084
  Discomfort 0.18±0.58 0.71±1.54 0.80±1.64* 0.35±1.01 0.26±0.79 0.37±1.19 0.0448

Abbreviations: ITT, intention to treat; scFOS, short-chain fructo-oligosaccharides.

Each symptom is scored between 1 and 10; data is expressed in arbitrary unit mean±s.d.

a,b,c

Desserts not sharing the same letter are significantly different (P<0.05, Dunnett's post hoc test vs the Control or Tukey's test among the five other mixtures).

*

Significant increase (Dunnett's test) in gastrointestinal symptom scores compared with 35 g dextrose, P<0.05. Other observed differences (Tukey's test) for flatulence at 24 h: maltitol 24–scFOS 11 vs scFOS 11 (P=0.0197); maltitol 17.5–scFOS 17.5 vs scFOS 11 (P=0.0005); maltitol 17.5–scFOS 17.5 vs maltitol 30–scFOS 5 (P=0.0377).