Table 2.
Genotyped SNPs | Chr a | Regulome DB Score b | TFBS c | Splicing (ESE or ESS) | Location | MAF d for Chinese in Database | % Genotyping Value |
---|---|---|---|---|---|---|---|
IL-1A: rs1800587 C/T | 2 | 5 | Y | Y | 5′ UTR | 0.073 | 99.92 |
IL-1B: rs16944 G/A | 2 | 1f | Y | — | 5′ near gene | 0.453 | 99.83 |
IL-6: rs1800796 C/G | 7 | 4 | Y | — | ncRNA | 0.233 | 99.75 |
IL-6R: rs7529229 T/C | 1 | 2b | — | — | intron | 0.442 | 98.59 |
IL-8: rs4073 T/A | 4 | 2b | Y | — | 5′ near gene | 0.389 | 98.84 |
IL-10: rs1800872 A/C | 1 | 5 | Y | — | 5′ near gene | 0.238 | 99.83 |
IL-10: rs1800896 A/G | 1 | 6 | Y | — | 5′ near gene | 0.059 | 99.83 |
Chr, chromosome;
TFBS: Transcription Factor Binding Site;
MAF: minor allele frequency.