Table 4.

Predicted active sites of the NBD protein, K71L and T204V mutants.

Protein	Site volume (cubic Å)	Protein volume (cubic Å)	Residues that forming pocket
NBD	434	34357	ASP10,LEU11,GLY12,THR13,THR14,TYR15,PHE68,ASP69,LYS71,ARG72,TRP90,THR145,VAL146,PRO147,ALA148,GLU175,PRO176,ILE197,PHE198,ASP199,GLY201,GLY202,GLY203,THR204,ASP206,VAL207,SER208,THR222,VAL337,VAL369
K71L	496	34418	ASP10,LEU11,GLY12,THR13,PRO14,TYR15,CYS17,ARG72,VAL146,PRO147,ALA148,TYR149,GLU175,PRO176,ALA179,ILE197,PHE198,ASP199,LEU200,GLY201,GLY202,GLY203,THR204,ASP206,VAL207,SER208,THR222,ALA223,GLY224,LYS271,ARG272,VAL337,GLY338,GLY339,GLY340,ALA368,VAL369,ALA370
T204V	532	34224	ASP10,LEU11,GLY12,THR13,THR14,TYR15,SER16,CYS17,LYS71,ARG72,VAL82,THR145,PRO147,ALA148,TYR149,PHE150,GLU175,ASP199,LEU200,GLY201,GLY202,GLY203,VAL204,PHE205,ASP206,ARG272,VAL337,GLY338,GLY339,PRO365,ASP366,GLU367,ALA368,VAL369,ALA370