Expression of Cyp4f18 in bone marrow neutrophils from Cyp4f18 +/+ (WT), +/− (HZ), and −/− (KO) mice.
(A) Total RNA was extracted from neutrophils and used as a substrate for reverse transcription. The cDNA was analyzed by PCR using primer pair exon7F-exon10R.
(B) Real time PCR analysis of neutrophil cDNA using a primer-probe set that is specific for Cyp4f18 transcripts containing exons 8 and 9.
(C) Extracts of membrane proteins (20 μg) from neutrophils were analyzed by western blot. CYP4F18 protein appears as a 60 kDa band in WT extracts.