Table 5.
Time of Reperfusion | Cyp4f18 +/+ (WT) | Cyp4f18 −/−(KO) | Sham WT | Sham KO | |
---|---|---|---|---|---|
Histological score of injury (1–6 scale) | 4 h | 2.6 ± 0.5 | 3.4 ± 0.5 | 1 | 1 |
12 h | 4.7 ± 0.4 | 4.7 ± 0.4 | 1 | 1 | |
24 h | 5.5 ± 0.29 | 5.25 ± 0.25 | 1 | 1 | |
| |||||
Cell infiltration: MPO+ cell number per hpf (0.22 mm2) | 12 h | 16.4 ± 5.1 | 18.7 ± 5.0 | 1 | 0.5 |
24 h | 25.2 ± 5.6 | 24.8 ± 5.4 | 2 | 2 | |
| |||||
BUN level (mg/dl) | 24 h | 146.7 ± 14.8 | 150.2 ± 14.8 | 22.2 | 17.8 |
Results are expressed as mean ± SEM, n = 5.