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. 2014 Feb 12;34(5):852–860. doi: 10.1038/jcbfm.2014.24

Figure 6.

Figure 6

Neocortical application of SR49059 (1 μmol/L) has no effect on the dehydration-induced suppression of the cerebral blood flow (CBF) response to whisker stimulation (A), acetylcholine (ACh) (B), and adenosine (C). Superfusion of the somatosensory cortex with losartan (5 μmol/L) tends to improve the dehydration-induced suppression of the CBF response to whisker stimulation (D) and ACh (E) at 24 hours (P>0.05 from time 0). The response to adenosine is not improved especially at 48 hours (F). *P<0.05, versus the corresponding vehicle (0 hour); analysis of variance and Tukey's test; n=5/group.