Table 1. Blood glucose and hormone concentrations.
| Group |
Glc (mg/dL) |
Epi (pg/mL) |
Glucagon (pg/mL) |
Cortisol (mg/dL) |
||||
|---|---|---|---|---|---|---|---|---|
| Eu | Hypo | Eu | Hypo | Eu | Hypo | Eu | Hypo | |
| Control | 92±4 | 50±4a | 23±12 | 559±232a | 85±18 | 134±37a | 29±9 | 29±11 |
| T1D w|o HAAF | 92±9 | 48±4a | 25±10 | 374±169a | 67±14 | 66±16b | 31±20 | 34±21 |
| T1D w| HAAF | 93±8 | 49±5a | 21±10 | 46±30b | 62±9b | 51±9b | 19±5 | 17±3 |
Summary of blood concentrations (mean±s.d.) of glucose (Glc) and counter-regulatory hormones epinephrine (Epi), glucagon and cortisol during euglycemia (Eu) and hypoglycemia (Hypo) per study group. Glc is the average of that measured from blood samples drawn from each subject concurrent with accumulation of the magnetic resonance spectroscopy data, i.e., a 11-minute span before discontinuation of dextrose and 16 minutes after blood glucose was first sampled at ⩽50 mg/dL. Hormone values represent the maximum concentration measured in each subject before and after discontinuation of dextrose.
a
Eu to Hypo: P<0.02.
b
T1D subgroup to control: P<0.05.