Figure 5.

Comparison of regional average (n=14) in vivo [¹¹C]SL25.1188 V_T, V_S, and BP_ND and in vitro concentration of monoamine oxidase B (MAO-B) determined by inmunoblotting in autopsied normal human brain (n=6) published previously by Tong.³⁵ Regions in order of in vitro concentration are cerebellar cortex, prefrontal cortex, temporal cortex, putamen, anterior cingulate cortex, thalamus, and caudate. Vertical lines represent the SD, lines represent the best linear fit (V_T: r²=0.9, P=0.001, V_S: r²=0.92, P=0.0006 and BP_ND: r²=0.7, P=0.02).