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. Author manuscript; available in PMC: 2014 May 8.
Published in final edited form as: J Immunol. 2010 Jun 23;185(3):1846–1854. doi: 10.4049/jimmunol.1001131

FIGURE 6. Sensitization of GPR17-deficient Mice with Df-pulsed WT BMDCs Enhances Pulmonary, LN, and Ig Responses upon Challenge.

FIGURE 6

(A) Inflammatory cell counts in BAL fluid. BMDCs from WT mice were pulsed with Df at 100 μg/ml for 24 h, and 104 cells were administered intranasally for sensitization into recipients of 4 genotypes. Recipients were challenged with 1 μg of Df intranasally at days 10 and 14 and were killed at day 16 for analyses. Total and differential cell counts for BAL fluid monocytes/macrophages (MΦs), neutrophils, eosinophils, and lymphocytes are shown. (B) Parabronchial LN cell numbers. Parabronchial LN cells were harvested and counted, and total cell numbers are shown. (C) Levels of total IgE and Df-specific IgG1 in serum. Total IgE and Df-specific IgG1 in sera of Df-challenged mice were measured by ELISA. Values are as the mean ± SEM (n = 5-12) combined from 3 independent experiments. *P < 0.01, #P < 0.05.