Table 3.

Significant GM volume reductions in HD patients compared with controls

Anatomical region		MNI coordinates			Z
		x	y	z
Putamen	L	−21	17	1	7.49
	R	18	10	1	7.06
Caudate, extends to thalamus	L	−10	16	4	7.41
	R	14	−3	19	6.80
Hippocampus	L	−30	−13	−11	5.03
	R	20	3	−24	5.02
Premotor cortex [BA 6]	L	−39	−15	55	5.19
Primary motor cortex [BA 4a]	L	−36	−19	55	5.26
Inferior parietal cortex	R	64	−27	27	5.21
Middle temporal gyrus	L	−48	−60	21	5.56
Lingual gyrus [BA 17]	L	−4	−82	0	5.27
Middle occipital gyrus [BA 18]	L	−26	−96	10	5.12
	R	20	−84	−11	5.13

VBM results are FWE corrected at P < 0.05 across the whole brain; Z, maximum Z-value for the anatomical area; BA, Brodmann area.