. 2014 Apr 17;12:8. doi: 10.1186/1477-9560-12-8

Table 1.

Current approval of the NOACs

	FDA Approval	EMA Approval
Dabigatran	-Stroke prevention in AF	-VTE prevention after orthopedic surgery,
Dabigatran	-Stroke prevention in AF	-Stroke prevention in AF
Rivaroxaban	-Stroke prevention in AF,	-VTE prevention afte orthopedic surgery
	-VTE prevention after orthopedic surgery	-Stroke prevention in AF
	- VTE treatment	-Stroke prevention in AF
Apixaban	-Stroke prevention in AF	-VTE prevention after orthopedic surgery
Apixaban	-Stroke prevention in AF	-Stroke prevention in AF

EMA = European Medicines Agency, AF = Non- valvular Atrial Fibrillation, VTE = Venous Thromboembolism to include Deep vein thrombosis and Pulmonary Embolism.