Table 4.
Prothrombin complex concentrates composition a
|
Prothrombin complex concentrate |
Factor levels (IU/ml) |
Protein levels ( IU/ml) |
Other |
||||||
|---|---|---|---|---|---|---|---|---|---|
| II | VII | IX | X | C | S | Z | ATIII | Heparin | |
|
3 Factor |
|
|
|
|
|
|
|
|
|
| Bebulin |
24-37 |
< 5 |
24-37 |
24-37 |
NA |
NA |
NO |
None |
< 0.15/IU FIX |
| Profilnine |
NMT 150/U/100 Factor IX U |
NMT 35/U/100 Factor IX U |
100 unit |
NMT 100/U/100 Factor IX U |
NA |
NA |
NA |
None |
None |
|
4 Factor |
|
|
|
|
|
|
|
|
|
| Beriplex |
20-48 |
10-25 |
20-31 |
22-60 |
22-31 |
17-19 |
Yes |
Yes |
Yes |
| Cofact |
30 |
13 |
23 |
26 |
4 |
21 |
Yes |
Yes |
None |
| Kcentra |
19-40 |
10-25 |
20-31 |
25-51 |
21-41 |
12-23 |
No |
Yes |
Yes |
| Octaplex |
31 |
16 |
22 |
24 |
12 |
24 |
Yes |
No |
Yes |
|
Activated PCC |
|
|
|
|
|
|
|
|
|
| FEIBA* | 1.3 IU/IU | 0.9 IU/IU | 1.4 IU/IU | 1.1 IU/IU | 1.1 IU/IU | NA | NA | No | No |
aAll concentrations are approximate and vary from one lot to another.
NMT = not more than, IU = international units.
*IU/IU = IU/FEIBA unit.