Table 4.
Relationship between CD147 and GLUT-1 expression and response to radiotherapy
Parameters | Patients (n=132) | CD147 expression | GLUT-1 expression | CD147 and GLUT-1 dual high expression | ||||||
---|---|---|---|---|---|---|---|---|---|---|
| ||||||||||
low expression | high expression | p-value | low expression | high expression | p-value | Yes | No | p-value | ||
Radiation sensitivity | <0.0011 | <0.0011 | <0.0011 | |||||||
radiation-resistant group | 47 | 4 | 43 | 5 | 42 | 39 | 8 | |||
radiation-sensitive group | 85 | 47 | 38 | 40 | 45 | 31 | 54 | |||
RT non-response | 0.0032 | 0.0092 | <0.0012 | |||||||
RT non-responsive subgroup | 9 | 0 | 9 | 0 | 9 | 9 | 0 | |||
radiation-sensitive group | 85 | 47 | 38 | 40 | 45 | 31 | 54 | |||
local recurrence | 0.0011 | 0.0071 | 0.0011 | |||||||
local recurrence subgroup | 17 | 2 | 15 | 2 | 15 | 14 | 3 | |||
radiation-sensitive group | 85 | 47 | 38 | 40 | 45 | 31 | 54 | |||
distant metastasis | <0.0011 | 0.0041 | 0.0011 | |||||||
distant metastasis subgroup | 22 | 2 | 20 | 3 | 19 | 17 | 5 | |||
radiation-sensitive group | 85 | 47 | 38 | 40 | 45 | 31 | 54 |
p value was estimated by chi-square test.
p value was estimated by Fisher’s exact test.
RT = Radiation therapy.