Fig. 4.

PSMβ1, PSMβ2 and their related variants upon exposure to challenged conditions. A, The molecular network resulting from ion clusters of PSMβ is shown. Nodes colored green are ion clusters found only in MRSA + vancomycin challenged conditions. Nodes colored gold are found only in MRSA samples. Nodes colored gray are found overlapping in MRSA alone samples and MRSA + daptomycin challenged conditions. Nodes labeled with only a sequence tag are within 500 ppm of the theoretical mass. Nodes labeled with sequence tags +numbers have their mass accuracy noted. B, Sequence of PSMβ1 (shown in bold) and related variants. Amino acid sequences for PSMβ1 are not shown in full form but are abbreviated at the N-terminal end. C, Sequence of PSMβ2 (shown in bold) and related variants. Amino acid sequences for PSMβ2 are not shown in full form but are abbreviated at the N-terminal end. Analysis of the all nodes in the different conditions containing dPSMs is provided in supplemental material. D, PSMβ1 variant VSIVENGVGLLGKLFGF and the peptide counts tested in 3 replicates under respective conditions.