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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Mol Genet Metab. 2013 Sep 19;111(2):116–122. doi: 10.1016/j.ymgme.2013.09.008

Figure 1. IDUA enzyme activity in multiple organs increased after a single injection of ~1.2 mg/kg laronidase.

Figure 1

A total of 28 age-matched mice were assigned into four groups: 1) MPS I mice (idua−/−, n=6, white columns) injected with 2 fold (~1.2 mg/kg) laronidase; 2) MPS I mice (n=6, dark columns)injected with normal-dose (0.58 mg/kg) laronidase; 3) MPS I mice (n=6, hatched columns) with no injections; 4) heterozygote (idua+/−, n=5, diamond columns) with no injections. Data are mean ±standard error. * p<0.05.