Table 1. Computed signal variability in the successive stages of synaptic transmission for a Calyx-of-Held type synapse (Coefficient of Variation, CV = SD/MEAN) driven by a 0.2 axon.

Stage	Signal	CV
Axon	AP width	6%
Pre-synaptic	Ca++ peak current	3%
Pre-synaptic	Ca++ influx	9%
Synapse	Peak [Ca++]	3%
Synapse	Vesicle release rate	10%
Synapse	Vesicles released	26%
Post-synaptic	EPSC amplitude	≈25%