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. 2014 May 8;10(5):e1003614. doi: 10.1371/journal.pcbi.1003614

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© 2014 Ronny Straube

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Comparison between predictions of the Batchelor-Goulian model and measurements in the PhoR/PhoB [26] and NRII/NRI systems [27]. (A) Symbols denote measurements of PhoB-P as a function of total PhoB amounts in the wild-type system (open squares) and in a mutant strain (filled circles) (data were taken from Fig. 4C in Ref. [26]). Solid lines were calculated from Eq. (31) with pmol, pmol and pmol, pmol. Note that (dotted lines) determines both, the threshold amount of total PhoB beyond which PhoB-P becomes constant as well as the value of that constant, as expected from Eq. (2). (B) Symbols denote in vitro measurements of NRI-P as a function of total NRI (reproduced from Fig. 4A in Ref. [27]). Solid line represents the best fit of the data to Eq. (3) with and , which indicates that the NRII/NRI system operates in the regime .

Inline graphic — Comparison between predictions of the Batchelor-Goulian model and measurements in the PhoR/PhoB [26] and NRII/NRI systems [27]. (A) Symbols denote measurements of PhoB-P as a function of total PhoB amounts in the wild-type system (open squares) and in a mutant strain (filled circles) (data were taken from Fig. 4C in Ref. [26]). Solid lines were calculated from Eq. (31) with pmol, pmol and pmol, pmol. Note that (dotted lines) determines both, the threshold amount of total PhoB beyond which PhoB-P becomes constant as well as the value of that constant, as expected from Eq. (2). (B) Symbols denote in vitro measurements of NRI-P as a function of total NRI (reproduced from Fig. 4A in Ref. [27]). Solid line represents the best fit of the data to Eq. (3) with and , which indicates that the NRII/NRI system operates in the regime .