. 2014 May 8;8(5):e2846. doi: 10.1371/journal.pntd.0002846

Table 3. Comparison of pre- and post-treatment GST-specific cytokine profiles at baseline by gender, age group and baseline S. haematobium infection status.

		Gender				Age group (years)						Baseline infection status
Pre-treatment		Male (n = 94)	Female (n = 101)	F_{1, 188}	p	4–9 (n = 77)	10–12 (n = 34)	13+ (n = 84)	F_{2, 188}	p	Un-infected (n = 93)	Infected (n = 102)	F_{1, 188}	p
PC1	Pro-inflammatory	0.115	−0.107	2.444	0.120	0.091	0.212	−0.169	2.166	0.117	0.059	−0.054	1.692	0.195
PC2	Th2/Regulatory	−0.063	0.058	0.753	0.387	0.071	−0.564	0.164	6.940	0.001 ^**	−0.034	0.031	1.286	0.258
PC3	Innate Inflammatory/Th1	0.038	−0.035	0.258	0.612	0.082	−0.293	0.043	1.838	0.162	0.022	−0.020	0.011	0.915

Cytokines are categorised according to the cellular phenotype with which they are most commonly associated. Mean pre- and post-treatment PC regression scores are indicated for each group. ANOVA (sequential sums of squares) analysis accounted for variation in PC scores due to gender and age group before baseline infection status,

*p<0.05,

**p<0.01.