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. 2014 May 8;10(5):e1004327. doi: 10.1371/journal.pgen.1004327

Figure 2. Mutations that perturb the abundance of Pms1 foci also perturb the abundance of Mlh2 foci.

Figure 2

(A) The percentages of nuclei containing Mlh2 foci were quantified in strains containing mutations in MMR genes or (B) genes encoding the catalytic subunits of the DNA polymerases Pol2 and Pol3. (C) Quantification of the percentages of nuclei containing Pms1 foci in an mlh2Δ strain. (D) Quantification of the percentages of nuclei containing Mlh2 foci in strains containing the pms1Δ mutation, the pms1Δ mutation in combination with an msh2Δ mutation or the endonuclease active site pms1 mutation pms1-E707K. Error bars indicate the SEM, and “n” indicates the numbers of cells examined.