Table 1. Ancestry adjusted ANOVA tests for association between Melanin Index (MI)a and genotypes in two admixed Brazilian populations.
Total sample (N = 500) | Gaucho (N = 352) | Baiano (N = 148) | |||||
Gene | SNP | F | p | F | p | F | p |
ADAM17 | rs1524668 | 0.578 | 0.562 | 0.817 | 0.443 | 0.331 | 0.719 |
AFG3L1 | rs4785763 | 0.167 | 0.846 | 0.116 | 0.891 | 0.090 | 0.914 |
ASIP | rs6058017 | 0.273 | 0.761 | 0.131 | 0.877 | 0.462 | 0.631 |
HERC2 | rs1129038 | 7.599 | 0.001 | 3.418 | 0.035 | 3.154 | 0.046 |
MC1R | rs1805009 | 4.436 | 0.036 | 6.698 | 0.010 | 0.096 | 0.758 |
MC1R | rs1805008 | 0.299 | 0.585 | 0.315 | 0.575 | b | b |
MC1R | rs1805007 | 0.267 | 0.605 | 0.440 | 0.507 | 0.498 | 0.482 |
OCA2 | rs1800407 | 8.195 | 0.004 | 3.656 | 0.057 | 6.073 | 0.015 |
OCA2 | rs1800401 | 0.262 | 0.770 | 0.803 | 0.371 | 0.018 | 0.982 |
OCA2 | rs1800414 | 0.863 | 0.353 | 0.892 | 0.346 | 0.036 | 0.850 |
SLC24A5 | rs1426654 | 30.816 | <0.001 | 21.946 | <0.001 | 10.441 | <0.001 |
SLC45A2 | rs6867641 | 0.400 | 0.671 | 0.444 | 0.642 | 9.795 | 0.089 |
SLC45A2 | rs26722 | 2.445 | 0.088 | 3.485 | 0.032 | 0.595 | 0.553 |
SLC45A2 | rs16891982 | 57.755 | <0.001 | 32.974 | <0.001 | 26.747 | <0.001 |
TPCN2 | rs3750965 | 0.642 | 0.527 | 0.814 | 0.444 | 0.079 | 0.924 |
TPCN2 | rs3829241 | 0.482 | 0.618 | 1.018 | 0.363 | 0.273 | 0.761 |
TYR | rs1042602 | 3.637 | 0.027 | 1.196 | 0.304 | 4.974 | 0.008 |
TYR | rs1126809 | 6.905 | 0.001 | 3.853 | 0.022 | 3.874 | 0.023 |
ANOVA tests performed on 1/MI.
Not tested due to scarcity of data (only n = 4 individuals with genotype CC).