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. 2014 May 8;9(5):e96886. doi: 10.1371/journal.pone.0096886

Table 1. Ancestry adjusted ANOVA tests for association between Melanin Index (MI)a and genotypes in two admixed Brazilian populations.

Total sample (N = 500) Gaucho (N = 352) Baiano (N = 148)
Gene SNP F p F p F p
ADAM17 rs1524668 0.578 0.562 0.817 0.443 0.331 0.719
AFG3L1 rs4785763 0.167 0.846 0.116 0.891 0.090 0.914
ASIP rs6058017 0.273 0.761 0.131 0.877 0.462 0.631
HERC2 rs1129038 7.599 0.001 3.418 0.035 3.154 0.046
MC1R rs1805009 4.436 0.036 6.698 0.010 0.096 0.758
MC1R rs1805008 0.299 0.585 0.315 0.575 b b
MC1R rs1805007 0.267 0.605 0.440 0.507 0.498 0.482
OCA2 rs1800407 8.195 0.004 3.656 0.057 6.073 0.015
OCA2 rs1800401 0.262 0.770 0.803 0.371 0.018 0.982
OCA2 rs1800414 0.863 0.353 0.892 0.346 0.036 0.850
SLC24A5 rs1426654 30.816 <0.001 21.946 <0.001 10.441 <0.001
SLC45A2 rs6867641 0.400 0.671 0.444 0.642 9.795 0.089
SLC45A2 rs26722 2.445 0.088 3.485 0.032 0.595 0.553
SLC45A2 rs16891982 57.755 <0.001 32.974 <0.001 26.747 <0.001
TPCN2 rs3750965 0.642 0.527 0.814 0.444 0.079 0.924
TPCN2 rs3829241 0.482 0.618 1.018 0.363 0.273 0.761
TYR rs1042602 3.637 0.027 1.196 0.304 4.974 0.008
TYR rs1126809 6.905 0.001 3.853 0.022 3.874 0.023
a

ANOVA tests performed on 1/MI.

b

Not tested due to scarcity of data (only n = 4 individuals with genotype CC).