Table 2. MI crude and ancestry-adjusted means, according to the genotypes of four polymorphisms for which an association with the Melanin Index (MI) was observed.
Polymorphisms and genotype | Total sample | Gaucho | Baiano | ||||||
N | MI mean | Adj MI meana | N | MI mean | Adj MI meana | N | MI mean | Adj MI meana | |
HERC2 rs1129038 | |||||||||
GG | 157 | 35.2 | 34.4 R | 65 | N/A | N/A | 92 | N/A | N/A |
GA | 140 | 32.8 | 32.6 S | 94 | N/A | N/A | 46 | N/A | N/A |
AA | 43 | 30.8 | 31.8 S | 40 | N/A | N/A | 3 | N/A | N/A |
GG | 23 | 49.8 | 38.7 R | 9 | 49.6 | 41.0 R | 14 | 49.9 | 41.7 R |
GA | 104 | 37.3 | 35.3 S | 51 | 34.9 | 34.0 S | 53 | 39.6 | 38.5 R |
AA | 366 | 32.1 | 32.0 T | 288 | 31.2 | 30.9 T | 78 | 35.4 | 34.9 S |
SLC45A2 rs16891982 | |||||||||
CC | 66 | 41.3 | 36.1 R | 24 | 39.7 | 35.4 R | 42 | 42.2 | 39.0 R |
CG | 164 | 36.1 | 34.9 R | 110 | 33.8 | 33.3 R | 54 | 41.0 | 39.4 R |
GG | 252 | 30.7 | 31.0 S | 209 | 30.5 | 30.3 S | 43 | 31.7 | 32.3 S |
TYR rs1126809 | |||||||||
GG | 338 | 34.8 | 33.4 R | 229 | N/A | N/A | 109 | N/A | N/A |
GA | 132 | 32.6 | 32.2 S | 98 | N/A | N/A | 34 | N/A | N/A |
AA | 18 | 30.0 | 30.5 S | 16 | N/A | N/A | 2 | N/A | N/A |
N/A = No association detected;
Means indicated by the same letter do not differ at the 0.05 level (Sidák-corrected multiple comparisons based on 1/MI).