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. 2014 May 8;9(5):e96982. doi: 10.1371/journal.pone.0096982

Figure 3. Effect of NCTD on the forming VM-like networks of the 3-D matrix of GBC-SD cells in vitro.

Figure 3

GBC-SD cell-formed networks in control group initiated formation within 48 hr after seeding the cells onto the matrix, matured basically after 1 week, with optimal structure formation achieved by two weeks; but in the process of network formation, using TIMP-2 or NCTD for 2 days, GBC-SD cells lost the capacity of the above vasculogenic-like network formation, with visible cell aggregation, float, nuclear fragmentation.