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. 2014 Jun;85(6):849–857. doi: 10.1124/mol.113.090654

TABLE 1.

Hepatotoxicity of Hsp90 inhibitors in the TAMH cell line

Data expressed as mean ± S.D. of three independent experiments.

Compound IC50 LC50
µM
17-DMAG 0.02 ± 0.01 0.21 ± 0.01
19Ph-DMAG 4.61 ± 0.39 13.83 ± 3.57
19Me-DMAG 8.00 ± 0.37 42.67 ± 0.16