Table 1.

Degradation half lives (h) of prodrugs at various pH values.

Prodrugs	pH 4	pH 5.5	pH 7.4
Ile-LPV	101 ± 29	53 ± 10	6.4 ± 0.3
Met-LPV	119 ± 6	55 ± 6	6.2 ± 0.4
Trp-LPV	123 ± 14	50 ± 9	5.4 ± 0.3