Table 2.
Parameters of the dose-response curves fitting with hormetic model of the individual OTA and ZEA effects on KK-1 cells and their concentrations in equieffective mixtures of two compounds.
| Mycotoxins | Dose-response models | Binary mixture ratios (µM) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| P1 a | P2 b | P3 c | P4 d | R2 e | Chi2/DoF f | EC1 | EC10 | EC25 | EC50 | |
| OTA | 0.00281 ± 0.0049 | 2.60 ± 4.07 | 2.04 ± 0.29 | 0.84 ± 0.10 | 0.9226 | 170.32 | 0.53 | 0.80 | 1.44 | 3.61 |
| ZEA | 0.00010 ± 0.0005 | 0.15 ± 0.11 | 15.97 ± 2.42 | 1.41 ± 0.14 | 0.9528 | 193.41 | 9.98 | 11.84 | 15.50 | 24.40 |
Notes: a,b,c,d Parameter for hormesis model, expressed with 95% confidence intervals; e,f Goodness of fit criteria of the function.