Table 3.
Inhibition level | HepG2 | KK-1 | |||||
---|---|---|---|---|---|---|---|
Observed inhibition effect | MDR CA | MDR IA | Observed inhibition effect | MDR CA | MDR IA | ||
1% | 3.85 | 2.15 | 0.52 | 2.33 | 2.36 | 0.85 | |
10% | 33.05 | 0.81 | 0.57 | 23.30 | 0.39 | 0.82 | |
25% | 50.17 | 0.78 | 0.87 | 56.31 | 0.35 | 0.78 | |
50% | 82.62 | 1.12 | 0.91 | 79.72 | 0.48 | 0.94 |
Note: Dark gray color indicates effect levels where the CA or IA prediction deviates by more than a factor of two (MDR > 2 or MDR < 0.5) from the experimental dose-response curves.