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. 2014 Mar 26;6(4):1177–1192. doi: 10.3390/toxins6041177

Table 3.

Calculated model deviation ratios (MDRs) at different observed effect levels (% effect) for the mixture.

Inhibition level HepG2 KK-1
Observed inhibition effect MDR CA MDR IA Observed inhibition effect MDR CA MDR IA
1% 3.85 2.15 0.52 2.33 2.36 0.85
10% 33.05 0.81 0.57 23.30 0.39 0.82
25% 50.17 0.78 0.87 56.31 0.35 0.78
50% 82.62 1.12 0.91 79.72 0.48 0.94

Note: Dark gray color indicates effect levels where the CA or IA prediction deviates by more than a factor of two (MDR > 2 or MDR < 0.5) from the experimental dose-response curves.