Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
CD16xCD33 BiKE enhances MDS-NK cell function against CD33+ targets. Resting PBMCs from normal donors and MDS patients were coated with 10 μg/mL of the CD16xCD33 BiKE or scFv CD16 control and cocultured with (A-C) or without (D-F) CD33+ HL-60 targets. NK cell CD107a expression and intracellular TNF-α and IFN-γ production were evaluated by FACS analysis (*P < .05, **P < .01, ***P < .001, ****P < .0001).
