Figure 2.

 Plasma glucose level at 3:00 am compared with bedtime and before breakfast. Plasma glucose levels were monitored at bedtime (9:00 pm), during the night (3:00 am) and before breakfast (7:00 am) in diabetic inpatients (n = 87) treated with bedtime NPH insulin or a long‐acting insulin analogue, with relatively stable glycemic control (bedtime glucose level 70–150 mg/dL). It is evident that the night time glucose level cannot be estimated from glucose levels at bedtime and/or before breakfast in some patients. Nocturnal hypoglycemia is seen in some patients, while in others an increase in glucose level with a nocturnal peak is observed.