Table 4. Comparison of clinical characteristics and clinical profile among groups according to HbA1c at admission.
| Groups (HbA1c at admission) | I (≤8.5%) | II (8.6–10.3%) | III (≥10.4%) | P |
|---|---|---|---|---|
| No. patients | 90 | 92 | 91 | |
| HbA1c (%) | 7.6 ± 0.1 | 9.5 ± 0.1* | 12.0 ± 0.1*† | <0.0001 |
| Sex (male/female) | 53/37 | 55/37 | 50/41 | |
| Age (years) | 64.2 ± 1.2 | 61.6 ± 1.3 | 57.6 ± 1.3* | 0.0011 |
| BMI (kg/m2) | 24.2 ± 0.3 | 24.1 ± 0.4 | 23.5 ± 0.4 | 0.3579 |
| Years from diagnosis | 11.7 ± 1.2 | 9.7 ± 0.8 | 7.4 ± 0.8* | 0.0088 |
| bSBP (mmHg) | 122.9 ± 1.4 | 120.6 ± 1.3 | 121.3 ± 1.4 | 0.4746 |
| DBP (mmHg) | 72.9 ± 1.2 | 72.7 ± 1.0 | 75.3 ± 0.9 | 0.1302 |
| sCre (mg/dL) | 0.74 ± 0.02 | 0.70 ± 0.02 | 0.63 ± 0.02*† | <0.0001 |
| FPG (mg/dL) | 134.2 ± 3.7 | 163.4 ± 3.9* | 195.0 ± 5.4*† | <0.0001 |
| PG‐6min (mg/dL) | 152.4 ± 3.9 | 178.7 ± 4.0* | 211.1 ± 5.6*† | <0.0001 |
| PPPG (mg/dL) | 223.3 ± 6.4 | 268.2 ± 7.7* | 323.7 ± 8.9*† | <0.0001 |
| FCPR (ng/mL) | 1.92 ± 0.10 | 1.84 ± 0.10 | 1.66 ± 0.11 | 0.2004 |
| CPR‐6min (ng/mL) | 3.85 ± 0.18 | 3.97 ± 0.19 | 3.66 ± 0.18 | 0.5467 |
| PPCPR (ng/mL) | 5.90 ± 0.29 | 4.88 ± 0.24* | 3.86 ± 0.18*† | <0.0001 |
Data are presented as mean ± SE.
*P < 0.01 vs group I, †P < 0.01 vs group II.
BMI, body mass index; CPR‐6min, C‐peptide immunoreactivity 6 min after intravenous injection of 1 mg glucagon; DBP, diastolic blood pressure; FCPR, fasting CPR; FPG, fasting plasma glucose; PG‐6min, plasma glucose 6 min after glucagon load; PPCPR, postprandial CPR; PPPG, postprandial plasma glucose; SBP, systolic blood pressure; sCre, serum creatinine. FPG and FCPR are values when meal load was carried out.