Table 5. Associations between retinal vessel diameters and various indices of incident obesity in the Funagata study population by sex.
| Indices of obesity | n | Affected (%) | Odds ratio (95% confidence interval) | |||||
|---|---|---|---|---|---|---|---|---|
| Crude | P‐value | Age adjusted | P‐value | Multivariable‐adjusted* | P‐value | |||
| Per 1 SD decrease in central retinal artery equivalent | ||||||||
| Male | ||||||||
| Obesity (BMI ≥ 25 kg/m2) | 130 | 15 (11.5) | 1.02 (0.57–1.81) | 1.01 (0.56–1.81) | 0.98 (0.44–2.18) | |||
| Overweight and obesity (BMI ≥ 23 kg/m2) | 77 | 11 (14.3) | 1.19 (0.61–2.33) | 1.36 (0.6–2.73) | 1.40 (0.54, 3.63) | |||
| Female | ||||||||
| Obesity (BMI ≥ 25 kg/m2) | 173 | 17 (9.82) | 0.94 (0.58–1.53) | 0.94 (0.57–1.54) | 1.48 (0.76–2.86) | |||
| Overweight and obesity (BMI ≥ 23 kg/m2) | 121 | 19 (15.7) | 0.76 (0.46–1.25) | 0.69 (0.41–1.16) | 0.73 (0.33–1.59) | |||
| Per 1 SD increase of central retinal vein equivalent | ||||||||
| Male | ||||||||
| Obesity (BMI ≥ 25 kg/m2) | 130 | 15 (11.5) | 0.91 (0.51–1.64) | 0.91 (0.51–1.65) | 0.82 (0.38–1.74) | |||
| Overweight and obesity (BMI ≥ 23 kg/m2) | 77 | 11 (14.3) | 0.86 (0.43–1.75) | 0.82 (0.42–1.63) | 1.13 (0.44–2.91) | |||
| Female | ||||||||
| Obesity (BMI ≥ 25 kg/m2) | 173 | 17 (9.82) | 1.56 (0.95–2.56) | 1.56 (0.94–2.57) | 2.10 (1.08–4.06) | 0.028 | ||
| Overweight and obesity (BMI ≥ 23 kg/m2) | 121 | 19 (15.7) | 1.71 (1.01–2.86) | 0.043 | 1.86 (1.07–3.24) | 0.027 | 1.81 (0.85–3.85) | |
BMI, body mass index. *Multivariable‐adjusted model: adjusted for age, sex, smoking status, mean arterial blood pressure, total plasma cholesterol, triglycerides and fasting plasma glucose.