Skip to main content
. 2013 Oct 21;14(1):110. doi: 10.1186/1465-9921-14-110

Figure 1.

Figure 1

Enhanced AHR in aging Cav1-/- mice. Total lung resistance in response to acetylcholine challenge was measured in Cav1-/- and WT mice at ages 1 month (A), 3 months old (B), 6 months old (C) and 12 months old (D). The log of the dose of acetylcholine required for a 200% increase in airway resistance over the baseline (log PC200 in μg/mL) was calculated for each mouse (E). Error bars indicate standard error. Significance was determined by 2 way ANOVA with a Bonferroni Post test (A-D) or a Student’s T test (E) using age matched Cav1-/- and WT mice. n = 4-9 *p < 0.05. **P < 0.01 and ***P < 0.001 between WT and Cav1-/-.