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. 2012 Aug 15;23(4):242–254. doi: 10.1089/hgtb.2012.073

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Copyright 2012, Mary Ann Liebert, Inc.

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FIG. 1. — Transduction efficiency and tropism in adult rats of lentiviral vectors containing the neuronal promoters. (A) Double immunofluorescence staining for the neuronal marker NeuN or (B) the astrocytic marker S100β, and AcGFPnuc after the injection of vesicular stomatitis virus G protein (VSV-G) pseudotyped lentiviral vectors (LVs) into the striatum. Acquisition parameters were optimized for each promoter. Quantification of AcGFPnuc-NeuN- and AcGFPnuc-S100β-positive cells are indicated and confirm the neuronal tropism of all vectors (n=5–6). Scale bar=20 μm.