FIG. 6.
In vivo expression of human VEGF165 persists at similar or higher levels than that of mouse VEGF over 2 weeks. In vivo expression by mV and hV clones was quantified immediately after cell injection (Day 0), after 1 (Day 7), or 2 weeks (Day 14), both by ELISA (A) and qRT-PCR (B) on whole-muscle extracts, confirming that expression of hV clones was similar or higher than the corresponding mV clone up to 2 weeks after implantation. Exo. VEGF, exogenous vector-derived VEGF; *p<0.05 and **p<0.01 vs mVhigh.