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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Hypertension. 2013 Dec 30;63(3):514–519. doi: 10.1161/HYPERTENSIONAHA.113.02164

Figure 2. Enhanced heart dysfunction and pulmonary congestion in DCMANP−/− mice.

Figure 2

A. Lung wet weight (LW), body weight (BW) and LW:BW ratio (n = 12–23 in each group). B&C. Histological evaluation of lung congestion by H&E stain. B. DCMANP+/+ mice have mild interstitial edema while DCMANP−/− mice show severe interstitial and intra-alveolar edema (pink area, asterisks); C. DCMANP−/− mice have more punctate hemorrhagic lesions in alveolar capillaries than DCMANP+/+ mice. Scale bars=200μm. D. Quantitative analysis of total alveolar congestion area per 20× field. Results are means of averages of 12 randomly selected fields from 3 to 4 mice in each group. ***p<0.001, **p<0.01, *p<0.05, nsp>0.05.